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Ten key points about COVID-19 in children: The shadows on the wall
Luis Escosa-García1, David Aguilera-Alonso2, Cristina Calvo1
1Department of Pediatrics, Infectious, and Tropical Diseases, La Paz Hospital, The Translational Research Network of Pediatric Infectious Diseases (RITIP), Madrid, Spain.
Insights
Children generally experience mild COVID-19 illness, but their role in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission is critical for public health strategies. Understanding pediatric COVID-19 is essential.
Area of Science:
- Pediatrics
- Infectious Diseases
- Epidemiology
Background:
- The COVID-19 pandemic, caused by SARS-CoV-2, presents unique challenges in understanding its impact on pediatric populations.
- Most existing literature on COVID-19 focuses on adult patients, leaving a knowledge gap regarding disease characteristics in children.
Purpose of the Study:
- To review and summarize the current literature on COVID-19 in children.
- To identify key characteristics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pediatric patients.
Main Methods:
- Expert review of peer-reviewed and preprint studies published between January 1, 2020, and May 28, 2020.
- Inclusion of relevant articles published after the specified period.
Main Results:
- Pediatric COVID-19 cases typically present with mild illness.
- Children appear to have a lower risk of severe complications and mortality compared to adults.
- The role of children in the transmission dynamics of SARS-CoV-2 requires further definition.
Conclusions:
- Children are generally less severely affected by COVID-19 but their transmission potential is a key factor in epidemiological models.
- Further research is needed to fully elucidate the impact of COVID-19 on children and their role in pandemic spread.
Abstract:
The pandemic of the new coronavirus disease-2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), initially described in China, is challenging the health care systems of all countries. Every emerging disease raises many questions with a scarcity of answers since all its characteristics are still being discovered. In the case of SARS-CoV-2, most of the literature comes from adult patients. Children seem to be less affected. Pediatric patients diagnosed with COVID-19 disease usually suffer a mild illness, with a low risk of complications, or mortality. Defining the role of children in the transmission of SARS-CoV-2 is critical as some national infection control decisions involving children, such as school closures or social distancing, will probably impact the dynamics of the virus. To aid in the knowledge of COVID-19 in children, this study presents an expert review of the literature published from 1 January to 28 May 2020, including peer-reviewed and preprint nonpeer-reviewed studies, along with some relevant articles afterward, summarizing ten key points that characterize the disease in children.
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