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Increasing adverse drug reaction reporting-How can we do better?
Miri Potlog Shchory1,2, Lee H Goldstein3, Lidia Arcavi4
1Department of Public Health, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Plos One
|August 14, 2020
Summary
Implementing an intervention program significantly increased adverse drug reaction (ADR) reporting among healthcare professionals. Lectures and accessible tools like telephone and online reporting were most effective in boosting ADR reporting rates.
Area of Science:
- Pharmacovigilance
- Healthcare Quality Improvement
- Patient Safety
Background:
- Adverse drug reactions (ADRs) contribute significantly to global morbidity and mortality.
- Existing national ADR reporting systems suffer from low reporting rates.
- Improving ADR reporting is crucial for enhancing patient safety and drug efficacy.
Purpose of the Study:
- To evaluate the effectiveness of an intervention plan designed to increase ADR reporting among physicians and nurses.
- To identify key factors and methods that can enhance ADR reporting in clinical settings.
Main Methods:
- A multicentre intervention study with one intervention group and two control groups.
- Phased approach: baseline data collection, intervention implementation, and follow-up.
- Intervention included posters, lectures, e-learning, and reminders; data collected via questionnaires on knowledge and behavior.
Main Results:
- The intervention group showed a 74-fold increase in ADR reports compared to the control group (adjusted OR = 74.1, p<0.001).
- Significant improvements were observed in knowledge related to behavior (p=0.01) and behavior related to reporting (p<0.001) in the intervention group.
- Specialist physicians, nurses, and those in additional roles reported higher rates; lectures were the preferred method, with telephone and online reporting being most convenient.
Conclusions:
- A continuous, sustained intervention program, managed by pharmacovigilance specialists, is effective in significantly improving ADR reporting rates.
- Targeted educational strategies, particularly lectures, and user-friendly reporting tools are essential for successful ADR reporting.
- Enhancing healthcare professionals' knowledge and behavior towards ADR reporting is achievable through structured interventions.
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