Clinical decision support tool for phototherapy initiation in preterm infants

Yassar Arain1,2, Juan M Banda3,4, Joshua Faulkenberry5

  • 1Division of Neonatal-Perinatal Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.

Insights

Implementing an electronic health record tool improved phototherapy guideline adherence in preterm infants. This clinical decision support (CDS) tool increased adherence by 77% without causing adverse events.

Area of Science:

  • Neonatal Medicine
  • Clinical Informatics
  • Pediatric Healthcare

Background:

  • Phototherapy is crucial for managing hyperbilirubinemia in preterm infants.
  • Initial adherence to phototherapy guidelines in academic NICUs was suboptimal (39%), with many infants receiving treatment below recommended total bilirubin (TB) thresholds.

Purpose of the Study:

  • To evaluate the impact of a novel electronic health record integrated clinical decision support (CDS) tool on phototherapy initiation adherence in preterm infants.
  • To determine if the CDS tool improved the proportion of phototherapy initiations consistent with recommended TB thresholds.

Main Methods:

  • Development and implementation of Premie BiliRecs (PBR), a CDS tool for preterm infants (27-34 weeks postmenstrual age).
  • Primary outcome: proportion of phototherapy initiation events aligned with recommended TB thresholds.

Main Results:

  • Adherence to phototherapy guidelines significantly increased to 69.8% (p < 0.001) after PBR implementation, a 77% improvement.
  • No significant increase in severe hyperbilirubinemia or the need for exchange transfusions was observed.

Conclusions:

  • The Premie BiliRecs (PBR) CDS tool effectively improved adherence to phototherapy guidelines in preterm infants.
  • The adoption of PBR enhanced guideline adherence without compromising infant safety or increasing adverse events.
Abstract