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Infective endocarditis in neonates

C O'Callaghan1, P McDougall

  • 1Department of Neonatology, Royal Children's Hospital, Melbourne, Australia.

Archives of Disease in Childhood
|January 1, 1988
PubMed

Insights

Neonatal infective endocarditis, often caused by Staphylococcus aureus, presents with sepsis signs. Echocardiography aids early diagnosis, improving outcomes for this rare neonatal condition.

Area of Science:

  • Neonatal Medicine
  • Infectious Diseases
  • Cardiology

Background:

  • Neonatal infective endocarditis is a rare but serious condition.
  • Staphylococcus aureus and Candida albicans are common causative agents.
  • Early diagnosis is crucial for improving patient survival rates.

Observation:

  • A review of five neonatal infective endocarditis cases was conducted.
  • Four cases were caused by Staphylococcus aureus, one by Candida albicans.
  • Clinical signs included septicaemia, positive blood cultures, thrombocytopenia, haematuria, and heart murmurs.

Findings:

  • Three patients developed early skin abscesses.
  • Two-dimensional echocardiography revealed bacterial vegetations in three cases.
  • Echocardiography detected vegetations even before a heart murmur was audible.

Implications:

  • Echocardiography, combined with specific clinical signs, can facilitate early diagnosis of neonatal endocarditis.
  • Prompt diagnosis and treatment are vital for improving survival in affected neonates.
  • This study highlights the utility of echocardiography in identifying endocarditis in neonates presenting with sepsis.

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