[Expert consensus on nutritional management of preterm infants with bronchopulmonary dysplasia]

Rong Zhang1, Xin-Zhu Lin, Yan-Mei Chang

  • 1Department of Neonatology, Children's Hospital of Fudan University, Shanghai 201102, China; 2. Department of Neonatology, Women and Children's Hospital, School of Medicine, Xiamen University, Xiamen, Fujian 361003, China; 3. Department of Pediatrics, Third Hospital, Peking University, Beijing 100191, China; 4. Department of Clinical Nutrition, Guangzhou Women & Children's Medical Center, Guangzhou 510623, China; 5. Department of Pediatrics, Chinese Academy of Medical Science Peking Union Medical College Hospital, Beijing 100730, China. tongxm2007@126.com.

Insights

Optimizing nutrition for preterm infants is crucial for preventing and managing bronchopulmonary dysplasia (BPD). Early and ongoing nutritional support improves lung development and neurological outcomes in infants with BPD.

Area of Science:

  • Neonatology
  • Pediatric Nutrition
  • Respiratory Medicine

Background:

  • Inadequate nutrition post-birth is a significant risk factor for bronchopulmonary dysplasia (BPD) in preterm infants.
  • Nutritional status is closely linked to BPD progression, clinical outcomes, and long-term prognosis.
  • Optimized nutritional support is vital for mitigating BPD severity and promoting lung and neurological development.

Purpose of the Study:

  • To establish an expert consensus on the nutritional management of bronchopulmonary dysplasia (BPD) in preterm infants.
  • To provide evidence-based guidelines for optimizing nutritional strategies in BPD care.
  • To address key aspects of nutrition from early postnatal life through post-discharge.

Main Methods:

  • Development of expert consensus using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology.
  • Comprehensive review of relevant studies from China and international sources.
  • Inclusion of seven critical aspects of BPD nutrition management.

Main Results:

  • The consensus highlights the critical role of nutrition in BPD management.
  • It details recommendations for fluid intake, energy requirements, and modes of feeding (enteral and parenteral nutrition).
  • Guidance is provided for post-discharge nutrition and ongoing monitoring and evaluation.

Conclusions:

  • Optimized nutritional support is essential for reducing BPD incidence and severity.
  • Comprehensive nutritional management, including post-discharge care, promotes better lung and neurological outcomes.
  • This consensus provides a framework for evidence-based BPD nutrition management.

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