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Updated: Dec 11, 2025

Simultaneous Measurement of Mitochondrial Calcium and Mitochondrial Membrane Potential in Live Cells by Fluorescent Microscopy
Published on: January 24, 2017
Mitochondrial calcium transport and permeability transition as rational targets for plant protection
1Departamento de Bioquímica, Facultad de Química, Universidad Nacional Autónoma de México, Ciudad Universitaria, 04510 México City, Mexico.
Abstract:
The mitochondrial permeability transition (MPT) is a death-inducing mechanism that collapses electrochemical gradients across inner mitochondrial membranes. Several studies in model plants have detailed potential MPT-dependent cell death upon abiotic stress in response to heat shock, ultraviolet radiation, heavy metal toxicity and waterlogging. However, the molecular specifics of the MPT and its possible role on plant cell death remain controversial. This review addresses previous and recent developments on the role(s) of the MPT in plants. Considering these advances, MPT targeting can constitute a plausible strategy to ameliorate cell death in plants upon abiotic stress.
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