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Updated: Dec 11, 2025

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Obstructive Sleep Apnea with Paradoxical Vocal Cord Movement in Children during Sleep Endoscopy: Case Series
Maxwell Newby1, Sarah Callaham2, Michele Carr3
1Department of Otolaryngology, West Virginia University, Morgantown, USA.
Insights
Pediatric obstructive sleep apnea (OSA) can involve paradoxical vocal cord movement (PVCM). Treatment of PVCM associated with OSA in children led to symptom resolution, indicating a link between these conditions.
Area of Science:
- Pediatric Sleep Medicine
- Otolaryngology
- Respiratory Physiology
Background:
- Obstructive sleep apnea (OSA) is a common sleep-related breathing disorder in children.
- Paradoxical vocal cord movement (PVCM) is typically associated with inspiratory stridor but can occur during sleep.
Observation:
- This study describes three pediatric cases of OSA with concurrent PVCM identified during drug-induced sleep endoscopy (DISE).
- Two patients had enlarged adenoids, while one had no other identified upper airway obstruction.
- PVCM was observed during sleep in the context of airway obstruction.
Findings:
- All three pediatric patients with OSA and PVCM experienced symptom resolution after treatment.
- Treatments included adenoidectomy with antireflux medications or proton pump inhibitors alone.
- Adenoidectomy and acid suppression appear effective in managing OSA with PVCM.
Implications:
- This case series suggests PVCM can be a component of pediatric OSA, occurring during sleep-related airway obstruction.
- Further research is needed to elucidate the etiology of PVCM in pediatric OSA.
- Understanding the link between PVCM and OSA may improve diagnostic and therapeutic strategies for affected children.
Objective:
To describe a series of pediatric cases of obstructive sleep apnea (OSA) with paradoxical vocal cord movement noted on drug-induced sleep endoscopy (DISE).
Materials And Methods:
Case series and chart review of children who had undergone DISE for OSA that showed PVCM.
Results:
Three cases where paradoxical vocal cord motion (PVCM) was noted during DISE are described. Two had an enlarged adenoid, and one had no other site of obstruction. Two were treated with adenoidectomy and antireflux medications. One received proton pump inhibitors alone. In all 3 cases, OSA symptoms resolved.
Conclusion:
This case series of documented obstructive sleep apnea related to paradoxical vocal cord movement suggests that this entity occurs during sleep with airway obstruction. Further clarification of etiology of PVCM during OSA and its management is needed.
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