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Updated: Dec 11, 2025

Biomimetic Materials to Characterize Bacteria-host Interactions
Published on: November 16, 2015
Bacteria mimics bearing carbohydrates, oligodeoxynucleotides and designed shapes
Jun Hu1, Yan Gu2, Mengjie Liu1
1Center for Soft Condensed Matter Physics and Interdisciplinary Research and School of Physical Science and Technology, Soochow University, Suzhou 215006, P. R. China. gchen@suda.edu.cn.
Abstract:
We utilize a facile and gentle strategy to fabricate bacteria mimics ("bacillus" and "coccus") endowed with carbohydrates, oligodeoxynucleotides and designed shapes via dopamine-polymer based nanoparticle fabrication and DNA-based multivalent interactions. These bacteria mimics with TLR- and CLR-targeted capabilities are demonstrated to exhibit enhanced immune stimulating efficiency.
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