Related Experiment Video
Updated: Dec 11, 2025

09:08
Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling
Published on: October 14, 2021
6.0K
How I Diagnose Primary Cutaneous Marginal Zone Lymphoma
Sarah E Gibson1, Steven H Swerdlow2
1Mayo Clinic Arizona, Phoenix.
American Journal of Clinical Pathology
|August 19, 2020
Summary
Diagnosing primary cutaneous marginal zone lymphoma (PCMZL) requires integrating histology, immunophenotyping, and clinical data. Distinguishing PCMZL from benign conditions and other lymphomas is crucial for appropriate patient management.
Area of Science:
- Dermatology
- Hematology
- Oncology
Background:
- Primary cutaneous marginal zone lymphoma (PCMZL) is a significant subtype of primary cutaneous B-cell lymphoma.
- Accurate diagnosis of PCMZL is challenging due to its differential diagnosis including benign lymphoproliferations and other cutaneous lymphomas.
Related Concept Videos
Skin Cancer
5.6K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.6K
Primary Lymphoid Organs
14.3K
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
14.3K

