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Primary diffuse large B-cell lymphoma of the mandible: A case report
Fatih Mehmet Coskunses1, Ülkem Cilasun2, Pinar Celik Topcu1
1Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Kocaeli University, Kocaeli, Turkey.
Introduction:
Lymphomas are a heterogeneous group of malignant neoplasms of lymphocytes and their precursor cells. Lymphoma is seen 3.5% of all intraoral malignancies and is the second most common neoplasm after the squamous cell carcinoma in the head and neck region. Diffuse large B-cell lymphomas (DLBCL), which is a subtype of non-Hodgkin lymphoma, are seen mostly in the paraoral region.
Case Presentation:
An 82-year-old woman was referred with a localised swelling of the mandibular buccal mucosa for 3 months. Excisional biopsy revealed the diagnosis of DLBCL in the mandible and chemotherapy regimen started immediately. However, patient died during treatment.
Conclusions:
Non-Hodgkin's lymphomas would be late- or misdiagnosed in the perioral region that may result poor prognosis.
