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Pentraxin-3 level in subarachnoid haemorrhage: Is it a prognostic factor?
Celal Kati1, Turker Yardan2, Hizir Ufuk Akdemir3
1Department of Emergency Medicine, Ondokuz Mayis University, Samsun, Turkey.
Objective:
The current study was planned to investigate the relationship of serum level of pentraxine-3 with various clinical and neurological scales and scores.
Methods:
The prospective case-control study was conducted at the Emergency Department of the Ondokuz Mayis University, Samsun, Turkey, from March 2013 to June 2014, and comprised subarachnoid haemorrhage patients and healthy. Pentraxine-3levels were measured from serum samples and compared with sub-groups of the various scales and scores used in the study. Data was analysed using SPSS 15.
Results:
Of the 77 subjects, 40(52%) were patients and 37(48%) were controls. Pentraxine-3levels in the cases were significantly higher than the controls (p<0.001). Among the cases, pentraxine-3level of the Glasgow Coma Scale sub-group was significantly different between the severe and mild categories (p=0.048). Likewise, pentraxine-3 levels were significantly different in terms of Fisher scale in patients with minor haemorrhage compared to those with massive haemorrhage (p=0.026). Also, pentraxine-3 levels were significantly higher in patients who died compared to those who fully recovered (p=0.042).
Conclusions:
There was found to be a relationship between pentraxine-3 level and the clinical severity of subarachnoid haemorrhage patients.
