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Updated: Dec 11, 2025

Analytical Techniques for Assaying Nitric Oxide Bioactivity
Published on: June 18, 2012
Effect and mechanism of cyclodextrins on nitrate reduction and bio-activity by S.oneidensis.MR-1
Jun Tu1, Jianbo Guo1, Caicai Lu2
1School of Environmental and Municipal Engineering, Tianjin Key Laboratory of Aquatic Science and Technology, Tianjin Chengjian University, Jinjing Road 26, Tianjin 300384, China.
Abstract:
Cyclodextrins (CDs) have been widely used due to the excellent solubilization of hydrophobic organics. However, their effect on the biotransformation process of hydrophilic pollutants is unclear. This study first evaluated the effect and mechanism of CDs on nitrate reduction by S.oneidensis.MR-1. The three CDs (α-CD, β-CD and γ-CD) all accelerated nitrate reduction, among which β-CD had the best effect. The nitrate reduction rate was increased by 21.8% with 0.5 mM β-CD. As for the mechanism, β-CD increased the biomass, membrane permeability and EPS of S.oneidensis.MR-1. The nitrate reductase activity was also increased by 1.34-fold with 0.5 mM β-CD. The current exchange density and the electron transfer system activity were increased by 11.4% and 99.5% in the β-CD-supply system, respectively. It confirmed that β-CD enhanced the biological and electrochemical characteristics and then enhanced bio-activity. This study provides a new understanding of CDs in microbial remediation and broadens the practical application.
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