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A novel technique for laser-assisted revascularization: an in vitro pilot study
Zacharia Mbaidjol1, Michael H Stoffel2, Martin Frenz3
1Department of Plastic and Reconstructive Surgery, University Hospital Bern, Freiburgstrasse, 3010, Bern, Switzerland. zahqaria@gmail.com.
Lasers in Medical Science
|August 20, 2020
Summary
A novel sutureless laser-assisted vascular anastomosis (LAVA) technique enables non-occlusive revascularization for cardiovascular diseases. This method creates a bypass circuit, potentially overcoming blood flow interruption limitations in surgical procedures.
Area of Science:
- Biomedical Engineering
- Cardiovascular Surgery
- Laser Medicine
Background:
- Surgical revascularization for severe tissue ischemia often requires temporary blood flow interruption.
- Existing methods face limitations in preventing ischemia during critical interventions.
Purpose of the Study:
- To introduce and evaluate a novel sutureless, non-occlusive revascularization technique.
- To establish a bypass circuit using laser-assisted vascular anastomosis (LAVA).
Main Methods:
- A 3-step technique using rabbit aorta to simulate side-to-side anastomosis.
- Laser-assisted vascular anastomosis (LAVA) with a diode laser (810 nm) and albumin solder patch.
- Channel creation using Holmium-doped YAG (Ho:YAG) or Xenon-Chloride (XeCl) laser.
Main Results:
- Successful creation of a functional bypass circuit allowing non-ischemic revascularization.
- Achieved average tensile strength of 2278.6 ± 800 mN with diode laser LAVA.
- Ho:YAG laser resulted in less anastomosis tension compared to XeCl laser.
- Histological analysis revealed minimal thermal damage and good tissue adaptation.
Conclusions:
- The developed sutureless LAVA technique provides a foundation for non-ischemic revascularization.
- This approach offers a promising alternative to traditional suture-based methods.
- Further studies are needed to optimize post-anastomotic flow parameters.
