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Bilateral Marginal Corneal Infiltrates: A Novel Ocular Manifestation of DRESS Syndrome
José Ignacio Vela1,2,3, Victoria Bulnes1, Nuria Torrell1
1Department of Opthalmology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Background:
Drug reaction with eosinophilia and systemic symptoms, known as DRESS syndrome, is a rare drug induced hypersensitivity reaction syndrome.
Methods:
case resport.
Results:
We describe a patient who presented with acute erythematous rash on her face, fever>38ºC, lymphadenopathy, blood abnormalities, and reaction suspected to be amoxicillin clavulanate-related. The patient also had an associated bilateral redness of the conjunctiva, peripheral corneal infiltrates, and anterior chamber with 3+ cells.
Conclusion:
We describe the first occurrence of bilateral marginal corneal infiltrates and acute anterior uveitis associated with amoxicillin clavulanate-induced DRESS syndrome and discuss its pathogenesis.
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