Related Experiment Video
Updated: Dec 11, 2025

05:55
Modeling the Functional Network for Spatial Navigation in the Human Brain
Published on: October 13, 2023
1.4K
The frequent complete subgraphs in the human connectome
Máté Fellner1, Bálint Varga1, Vince Grolmusz1,2
1PIT Bioinformatics Group, Eötvös University, Budapest, Hungary.
Plos One
|August 21, 2020
Summary
Researchers mapped frequent complete subgraphs in human brain networks using diffusion MRI. They identified distinct subgraph patterns more common in male and female connectomes, revealing robust substructures.
Area of Science:
- Neuroscience
- Graph Theory
- Medical Imaging
Background:
- The human connectome, representing brain networks, can be mapped using diffusion MRI.
- Nodes represent brain regions, and edges represent connecting axonal fibers.
- Previous work has explored graph-theoretical properties of human connectomes.
Purpose of the Study:
- To map frequent complete subgraphs within human brain networks.
- To identify sex differences in the prevalence of these subgraphs.
- To establish robust substructures in brain graphs resistant to artifacts.
Main Methods:
- Applied diffusion MRI-based techniques to map the human connectome.
- Utilized graph theory to analyze network structures.
- Identified complete subgraphs present in at least 80% of the analyzed brain graphs.
Main Results:
- Identified 812 complete subgraphs more frequent in male connectomes.
- Identified 224 complete subgraphs more frequent in female connectomes.
- Established robust substructures by using a high frequency threshold (80%).
Conclusions:
- Frequent complete subgraphs represent robust substructures within the human connectome.
- Significant sex differences exist in the prevalence of specific brain network substructures.
- This mapping provides insights into the structural organization of male and female human brain networks.
More Related Videos
Related Concept Videos
Anatomy of the Brain: Major Regions
9.0K
The brain is the most complex organ in the human body. It consists of four main parts: the cerebrum, diencephalon, cerebellum, and brainstem.
The cerebrum is the largest section of the brain and divides into left and right hemispheres, separated by a deep fissure. The cerebral outer layer of grey matter — the cerebral cortex — comprises elevations called gyri and shallow groves called sulci. The inner portion of white matter includes long nerve fibers known as axons, which connect...
The cerebrum is the largest section of the brain and divides into left and right hemispheres, separated by a deep fissure. The cerebral outer layer of grey matter — the cerebral cortex — comprises elevations called gyri and shallow groves called sulci. The inner portion of white matter includes long nerve fibers known as axons, which connect...
9.0K
Organization of the Brain
2.0K
The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
2.0K
Neuron Structure
17.1K
Neurons are the main type of cell in the nervous system that generate and transmit electrochemical signals. They primarily communicate with each other using neurotransmitters at specific junctions called synapses. Neurons come in many shapes that often relate to their function, but most share three main structures: an axon and dendrites that extend out from a cell body.
Structure and Function of Neurons
The neuronal cell body—the soma— houses the nucleus and organelles vital to...
Structure and Function of Neurons
The neuronal cell body—the soma— houses the nucleus and organelles vital to...
17.1K
Neuron Structure
229.6K
Overview
229.6K
Neural Circuits
2.4K
Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
2.4K
Association Areas of the Cortex
8.2K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
8.2K

