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Published on: August 7, 2017
On the Increased and Decreased Structural Connectivity of the Demented Human Brain
Daniel Hegedus1, Marton Barnabas Mora1, Balint Varga1
1PIT Bioinformatics Group, ELTE Eötvös Loránd University, H-1117 Budapest, Hungary.
None:
With the enormous advances in cerebral imaging techniques, a large amount of data is available for studying the aging and demented brain. In this contribution, we apply the OASIS-3 dataset for identifying small areas of the human gray matter, which have higher- or lower structural connectivity in dementia and aging. As anticipated, we found that finer structures of the hippocampus and the temporal lobe show decreased connectivity in dementia. More surprisingly, the precuneus, the cuneus, and finer structures in the insula show higher connectivity in dementia than in the healthy state.
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