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Congenitally corrected transposition of the great arteries

Tracy Halvorson1, John Blau1, Dennis Firchau1

  • 1Department of Pathology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242.

Cardiovascular Pathology : the Official Journal of the Society for Cardiovascular Pathology
|August 21, 2020
PubMed

Insights

Congenitally corrected transposition of the great arteries (cc-TGA) is a rare heart defect. This autopsy case highlights cc-TGA pathology and the risk of fatal arrhythmias in affected adults.

Area of Science:

  • Cardiology
  • Pathology
  • Medical Genetics

Background:

  • Congenitally corrected transposition of the great arteries (cc-TGA), or L-transposition, is a rare congenital heart defect affecting approximately 0.5% of cases.
  • cc-TGA is defined by atrioventricular and ventriculoarterial discordance, leading to abnormal blood flow through the heart.
  • Patients with cc-TGA have an increased risk of cardiac arrhythmias due to conduction system abnormalities.

Keywords:
Cardiac pathologyCongenital heart diseaseL-transpositioncc-TGA

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