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Two new pyranoxanthones from the stem bark of Calophyllum pseudomolle P.F. Stevens
Mulyadi Tanjung1, Tjitjik Srie Tjahjandarie1, Ratih Dewi Saputri1
1Natural Products Chemistry Research Group, Organic Chemistry Division, Faculty of Science and Technology, Department of Chemistry, Universitas Airlangga, Surabaya, Indonesia.
Abstract:
Two new pyranoxanthones, calotetrapterins D (1) and E (2), were isolated from the stem bark of Calophyllum pseudomolle P.F. Stevens along with α-mangostin (3). The structures of compounds 1-2 were determined based on 1D NMR (1H, 13C) and 2D NMR (HMQC, HMBC), as well as HRESIMS spectroscopic analysis. Compounds 1-2 showed moderate activity against HeLa and murine leukaemia P-388 cells.
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