Proteomics-Based Methodologies for the Detection and Quantification of Seafood Allergens.

Area of Science:

• Food Science
• Allergology
• Analytical Chemistry

Background:

• Seafood is a major food allergen source, posing significant risks globally.
• Accurate detection of seafood allergens in food is crucial for public health.
• European Food Safety Authority (EFSA) highlights the need for advanced control methodologies.

Purpose of the Study:

• To provide a comprehensive review of proteomics applications for seafood allergen detection.
• To detail discovery and targeted proteomics strategies for seafood allergy studies.
• To offer insights into future directions and new perspectives in the field.

Main Methods:

• Review of existing literature on proteomics methodologies.
• Analysis of discovery proteomics for initial allergen identification.
• Examination of targeted proteomics for precise allergen quantification.

Main Results:

• Proteomics offers accurate, sensitive, and fast methods for seafood allergen detection.
• Both discovery and targeted proteomics are valuable for seafood allergy management.
• The review synthesizes current knowledge and identifies research gaps.

Conclusions:

• Proteomics is a powerful tool for seafood allergen detection and quantification.
• Advanced detection methods are essential for effective seafood allergy control.
• Further research in proteomics will enhance food safety and allergen management strategies.