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Polysaccharides from Auricularia auricula: Preparation, structural features and biological activities
Nana Chen1, Hao Zhang2, Xin Zong1
1Key Laboratory of Molecular Animal Nutrition, Ministry of Education, College of Animal Sciences, Zhejiang University, Hangzhou 310058, China.
This review summarizes research on Auricularia auricula polysaccharides (AAPs), highlighting their extraction, structure, biological functions, and mechanisms. It provides insights into AAP structure-activity relationships for future studies.
Area of Science:
- Pharmacology
- Mycology
- Biochemistry
Background:
- Auricularia auricula, a traditional edible fungus, possesses significant nutritional and pharmacological value.
- Polysaccharides from Auricularia auricula (AAPs) are key bioactive compounds with diverse biological functions.
Purpose of the Study:
- To systematically review current research on AAPs, covering extraction, purification, structural characteristics, and biological activities.
- To explore potential molecular mechanisms and structure-activity relationships of AAPs.
- To identify future research directions for AAPs.
Main Methods:
- Systematic literature review of studies on Auricularia auricula polysaccharides.
- Analysis of extraction and purification techniques.
- Evaluation of reported structural features and biological activities.
Main Results:
- AAPs exhibit a range of biological functions, supported by accumulating evidence.
- Understanding of AAP structural features and their relationship to biological activity is evolving.
- Potential molecular mechanisms underlying AAP functions are being elucidated.
Conclusions:
- This review consolidates current knowledge on AAPs, including their extraction, structure, and bioactivities.
- The findings highlight the importance of AAP structure-activity relationships for understanding their therapeutic potential.
- Further research into AAPs is warranted to fully explore their applications.
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