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Oral Lichen Planus and Polycythemia: Possible Association
Yassine Oueslati1,2, Raouaa Belkacem Chebil1,2, Haifa Regaieg3
1Department of Oral Medicine and Oral Surgery, SAHLOUL Hospital (Sousse), Dental Faculty of Monastir, University of Monastir, Tunisia.
Case Reports in Dentistry
|August 25, 2020
Summary
Oral lichen planus and polycythemia, rarely associated conditions, were observed together in a patient. Both immune-mediated diseases may share underlying pathogenic similarities warranting further investigation.
Area of Science:
- Immunology
- Hematology
- Oral Medicine
Background:
- Oral lichen planus (OLP) is a chronic immune-mediated inflammatory condition affecting oral mucosa.
- Polycythemia is a myeloproliferative disorder characterized by increased red blood cell mass and potential overproduction of granulocytes and platelets.
- The co-occurrence of OLP and polycythemia is infrequently documented in scientific literature.
Observation:
- This paper reports the rare simultaneous occurrence of oral lichen planus and polycythemia in a 52-year-old male patient.
- The patient presented with clinical manifestations of both conditions.
Findings:
- While a causal link is not established, OLP and polycythemia share potential similarities in immune dysregulation and pathogenesis.
- Clinical features of both diseases may overlap, suggesting a possible connection.
Implications:
- The presence of oral lesions may serve as an early indicator for identifying and diagnosing polycythemia.
- Early diagnosis and intervention for these conditions can prevent complications and improve patient outcomes.
- Further research is needed to elucidate the potential shared immunological pathways and confirm the association between OLP and polycythemia.
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