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Updated: Dec 11, 2025

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
A rare case of intestinal obstruction: Sclerosing encapsulating peritonitis of unknown cause
1Department of Emergency Medicine, Jeju National University School of Medicine, Jeju-do, Republic of Korea.
Abstract:
Sclerosing encapsulating peritonitis (SEP) is characterized by the partial or complete enclosing of the small intestines by a thick fibro-collagenous membrane, which can cause recurrent intestinal obstruction. SEP is a clinically rare disease, and the major risk factor is peritoneal dialysis (PD). Early diagnosis of SEP is an important factor in the patient's prognosis, but it is clinically difficult. A 52-year-old woman visited the emergency department (ED) with a 2-day history of abdominal pain and vomiting. She had a history of liver cirrhosis with chronic hepatitis B, but no history of PD, and she underwent a biopsy of the peritoneum by laparoscopy a month ago. On physical examination, there were peritoneal irritation signs on the right lower quadrant (RLQ). Abdominal computed tomography (CT) showed dilated small intestinal loops clustered in the RLQ, which were surrounded by a sac-like, thick fibrous membrane. Based on CT findings, small intestinal obstruction due to SEP was early diagnosed in the ED. Emergency physicians should include SEP in the differential diagnosis of the cause of intestinal obstruction. Abdominal CT is a useful modality for the early diagnosis of SEP in the ED.
Insights
Sclerosing encapsulating peritonitis (SEP) can cause intestinal obstruction. Abdominal CT scans aid in the early diagnosis of this rare condition, even without a history of peritoneal dialysis.
Area of Science:
- Gastroenterology
- Radiology
Background:
- Sclerosing encapsulating peritonitis (SEP) is a rare condition causing intestinal obstruction.
- Peritoneal dialysis (PD) is a major risk factor for SEP.
- Early diagnosis of SEP is crucial for patient prognosis but often challenging.
Observation:
- A 52-year-old woman presented with abdominal pain and vomiting.
- She had a history of liver cirrhosis and recent peritoneal biopsy, but no PD history.
- Physical exam revealed right lower quadrant peritoneal irritation signs.
Findings:
- Abdominal CT demonstrated dilated small intestinal loops clustered in the RLQ.
- A sac-like, thick fibrous membrane surrounded the intestinal loops.
- CT findings led to an early diagnosis of SEP-induced small intestinal obstruction in the ED.
Implications:
- Emergency physicians should consider SEP in the differential diagnosis of intestinal obstruction.
- Abdominal CT is a valuable tool for the early detection of SEP in emergency settings.
- This case highlights SEP diagnosis in a patient without typical risk factors.
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