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Updated: Dec 11, 2025

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Improving Student Outcomes with an Adaptable Molecular Cloning Course-Based Undergraduate Research Experience
Published on: November 15, 2024
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NeuroLab Research Experiences: Extending the CURE Design Framework into an Informal Science Setting Dedicated to
Ralph Imondi1, Kristin M Bass2, Ruchita Patel2
1Coastal Marine Biolabs Integrative Biosciences Institute, Ventura Harbor, CA.
Summary
This study adapted the course-based undergraduate research experiences (CURE) framework for high school students, bridging genomics and neuroscience. It shows CUREs can effectively engage younger learners in authentic scientific research.
Area of Science:
- Comparative functional genomics
- Developmental neuroscience
- Life science education
Background:
- Course-based undergraduate research experiences (CUREs) are effective learning models for broadening participation in scientific research.
- Existing CURE models are predominantly implemented in four-year higher education institutions for undergraduate students.
Purpose of the Study:
- To adapt the CURE design framework for a structured instructional intervention for upper-level high school students.
- To demonstrate the feasibility of using the CURE framework for informal science programs targeting younger learners.
- To make life science research more accessible to high school students.
Main Methods:
- Utilized the CURE design framework to structure an instructional intervention.
- Engaged upper-level high school students in basic research.
- Bridged comparative functional genomics and developmental neuroscience topics.
Main Results:
- The intervention successfully engaged high school students in authentic research.
- Preliminary data indicate positive effects on student self-efficacy in scientific research.
- The program enhanced students' collaborative abilities and understanding of scientific knowledge construction.
Conclusions:
- The CURE framework is a feasible and effective model for high school science education.
- This approach can broaden access to life science research for younger learners.
- The intervention shows promise for improving students' research skills and scientific literacy.
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