Related Experiment Video

Updated: Dec 11, 2025

Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses
11:48

Generation, Amplification, and Titration of Recombinant Respiratory Syncytial Viruses

Published on: April 4, 2019

16.8K

[Rare viral infections of the lungs]

F Pfäfflin1, H Flick2, M Vogtmann1

  • 1Medizinische Klinik mit Schwerpunkt Infektiologie und Pneumologie, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Deutschland.

Der Pneumologe
|August 25, 2020
PubMed

Insights

Four rare but severe viral lung infections—avian influenza, Middle East respiratory syndrome (MERS), Hantavirus, and measles—can cause serious pulmonary complications. Understanding their epidemiology, clinical course, treatment, and prevention is crucial for public health in Germany.

Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Public Health

Context:

  • The lungs' direct environmental exposure makes them susceptible to diverse viral pathogens.
  • Four specific viruses, though rare in Germany, can cause significant pulmonary disease: avian influenza, Middle East respiratory syndrome (MERS), Hantavirus, and measles.
  • These pathogens pose risks due to potential for severe pulmonary complications and high mortality.

Purpose:

  • To detail the epidemiology, clinical presentation, treatment strategies, and preventive measures for four underrecognized viral pathogens causing lung disease.
  • To enhance awareness among healthcare professionals regarding avian influenza, MERS, Hantavirus, and measles.
  • To provide essential knowledge for managing potential outbreaks of these rare but dangerous infections.

Summary:

  • Avian influenza, MERS, and Hantavirus are zoonotic, while measles is human-to-human transmitted.
  • All four viral infections can lead to severe pulmonary manifestations and carry a high mortality rate.
  • Measles, MERS, and avian influenza present significant public health concerns due to their potential for widespread transmission.

Impact:

  • Increased preparedness for rare but severe pulmonary viral infections in Germany.
  • Improved clinical recognition and management of avian influenza, MERS, Hantavirus, and measles.
  • Strengthened public health strategies to mitigate the impact of emerging and re-emerging infectious diseases.
Keywords:
Avian influenzaHantavirusMeaslesMiddle East respiratory syndromePneumonia

More Related Videos

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection09:01

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection

Published on: December 10, 2013

8.2K
Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria11:32

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria

Published on: February 23, 2014

15.4K

Related Concept Videos

Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
583
Pulmonary Cycle: Exhalation01:17

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
2.7K
Viral Recombination00:57

Viral Recombination

Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
24.6K
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps:
2.2K
Common Respiratory Disorders01:31

Common Respiratory Disorders

Respiratory disorders, a prevalent health concern globally, are generally divided into two primary categories: upper and lower respiratory tract disorders. The categorization is based on the area of the respiratory system they affect.
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
1.1K
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
1.4K