Related Experiment Video

Updated: Dec 11, 2025

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses
03:53

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Published on: November 10, 2023

1.7K

The rise and evolution of COVID-19

Mohsen Baghchechi1, Navin Jaipaul2,3,4, Sharon E Jacob3,4,5

  • 1University of California, School of Medicine, Riverside, CA, USA.

International Journal of Women'S Dermatology
|August 25, 2020
PubMed

Insights

Skin manifestations like rashes and "COVID toes" can appear in children and adolescents with COVID-19, sometimes before respiratory symptoms. Dermatologists can help identify the disease through these cutaneous findings.

Area of Science:

  • Virology
  • Dermatology
  • Epidemiology

Background:

  • Coronaviridae (CoV) are zoonotic viruses causing illnesses from common colds to severe epidemics.
  • A novel coronavirus caused the 2019 COVID-19 pandemic, necessitating rapid containment and early detection strategies.
  • Understanding disease hallmarks is crucial for management and triage during the COVID-19 outbreak.

Purpose of the Study:

  • To investigate the association between COVID-19 and cutaneous findings.
  • To highlight the potential role of dermatologists in identifying COVID-19 through skin manifestations.
  • To document the timing and presentation of skin conditions in relation to COVID-19 illness.

Main Methods:

  • Review of clinical presentations and case reports of COVID-19 patients.
  • Analysis of documented cutaneous findings in individuals with confirmed COVID-19.
  • Correlation of skin symptom onset with respiratory symptom onset and recovery phases.

Main Results:

  • Common cutaneous findings include maculopapular rashes, livedo reticularis, and acro-ischemic lesions ('COVID toes').
  • These skin manifestations were observed in pediatric and adolescent populations, predominantly.
  • Skin findings appeared at various times, from preceding respiratory symptoms to weeks post-recovery.

Conclusions:

  • Cutaneous presentations are significant indicators of COVID-19, particularly in younger populations.
  • Dermatological assessment can aid in the early detection and diagnosis of COVID-19.
  • The role of dermatologists is expanded in managing and identifying COVID-19 through its dermatological manifestations.

Keywords:
CoronavirusCutaneousInflammationPandemic

More Related Videos

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-208:41

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

Published on: November 5, 2021

3.1K
Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples09:26

Quantification and Whole Genome Characterization of SARS-CoV-2 RNA in Wastewater and Air Samples

Published on: June 30, 2023

1.5K

Related Concept Videos

Viral Mutations00:36

Viral Mutations

A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
39.1K
Viral Recombination00:57

Viral Recombination

Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
24.6K
Infection01:20

Infection

When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
11.3K
Steps in Outbreak Investigation01:18

Steps in Outbreak Investigation

In the ever-evolving field of public health, statistical analysis serves as a cornerstone for understanding and managing disease outbreaks. By leveraging various statistical tools, health professionals can predict potential outbreaks, analyze ongoing situations, and devise effective responses to mitigate impact. For that to happen, there are a few possible stages of the analysis:
401
What is Evolutionary History?02:35

What is Evolutionary History?

Scientists record evolutionary history by analyzing fossil, morphological, and genetic data. The fossil record documents the history of life on Earth and provides evidence for evolution. However, both fossil and living organisms offer evidence that outlines Earth’s evolutionary history.
42.4K
Eukaryotic Evolution01:24

Eukaryotic Evolution

The endosymbiont theory is the most widely accepted theory of eukaryotic evolution; however, its progression is still somewhat debated. According to the nucleus-first hypothesis, the ancestral prokaryote first evolved a membrane to enclose DNA and form the nucleus. Conversely, the mitochondria-first hypothesis suggests that the nucleus was formed after endosymbiosis of mitochondria.
Contrary to the endosymbiont theory, the eukaryote-first hypothesis proposes that the simpler prokaryotic and...
39.7K