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Anticoagulation practice patterns in COVID-19: A global survey
Rachel P Rosovsky1, Kristen M Sanfilippo2, Tzu Fei Wang3
1Department of Medicine Massachusetts General Hospital Harvard Medical School Boston MA USA.
Research and Practice in Thrombosis and Haemostasis
|August 25, 2020
Summary
Current practices for managing venous thromboembolism (VTE) in COVID-19 patients vary globally. Most physicians use prophylactic anticoagulation, but more research is needed to establish optimal VTE and bleeding management strategies.
Area of Science:
- Internal Medicine
- Hematology
- Infectious Diseases
Background:
- Optimal management of venous thromboembolism (VTE) in coronavirus disease 2019 (COVID-19) patients remains unclear due to limited data.
- Understanding current global practices is crucial for guiding future research.
Purpose of the Study:
- To assess worldwide physician practices in preventing, diagnosing, and managing VTE in COVID-19 patients.
- To gather insights for designing prospective and randomized clinical trials.
Main Methods:
- An online survey was distributed to physicians internationally.
- The survey focused on prophylaxis, diagnosis, and treatment of VTE in COVID-19 patients.
- Data were collected from April 10-14, 2020.
Main Results:
- 515 physicians from 41 countries responded.
- 78% recommended prophylactic anticoagulation for hospitalized COVID-19 patients, primarily using heparin-based treatments.
- Observed thrombotic complications (e.g., pulmonary embolism) and bleeding complications were reported, with wide variations in incidence estimates.
Conclusions:
- Significant variation exists in VTE management approaches for COVID-19 patients.
- There is an urgent need for well-designed epidemiologic studies and randomized clinical trials to determine optimal anticoagulation strategies and understand VTE/bleeding risks.
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