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[SARS-CoV-2 and Perinatal Aspects].

Ann Carolin Longardt1, Vincent Patrick Winkler2, Ulrich Pecks2

  • 1Klinik für Kinder- und Jugendmedizin I / Neonatologie, Universitätsklinikum Schleswig-Holstein, Kiel.

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This summary is machine-generated.

Pregnant women with SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection generally have good outcomes, with no evidence of significant adverse effects on mothers or newborns. Newborn infections are rare and typically mild.

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Area of Science:

  • Infectious Diseases
  • Maternal-Fetal Medicine
  • Neonatology

Background:

  • The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic presents numerous unknowns, particularly concerning vulnerable populations.
  • Pregnant women and newborns require specific consideration due to unique physiological states and limited available data.

Purpose of the Study:

  • To review current data on SARS-CoV-2 in pregnancy, labor, and newborns.
  • To inform and improve guidance, treatment, and future research for this patient group.

Main Methods:

  • Systematic review of existing literature on SARS-CoV-2 in pregnant women and neonates.
  • Analysis of transmission routes, clinical manifestations, and maternal/perinatal outcomes.

Main Results:

  • No current evidence suggests significant unfavorable maternal or perinatal outcomes in SARS-CoV-2-infected pregnant individuals.
  • Many pregnant women with SARS-CoV-2 remain asymptomatic; vertical transmission is possible but rare.
  • Neonatal SARS-CoV-2 infections are infrequent, generally mild, and predominantly present with respiratory symptoms.

Conclusions:

  • Current data indicate a generally favorable prognosis for pregnant women and newborns affected by SARS-CoV-2.
  • Further research is needed to fully understand and manage SARS-CoV-2 in this population.