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Updated: Dec 11, 2025

Preparation of a Blood Culture Pellet for Rapid Bacterial Identification and Antibiotic Susceptibility Testing
Published on: October 15, 2014
Prognostic Value Of Blood Cultures as an Illness Severity Marker In Emergency Medical Admissions
R Conway1, B O'Connell2, D Byrne3
1PhD MRCPI, MED Directorate, St James's Hospital, Dublin 8, Ireland.
Background:
Positive blood cultures predict mortality. The prognostic value of blood culture performance itself has not been fully defined.
Methods:
We evaluated medical admissions from 2002-2017. We defined blood culture category as 1) no culture 2) negative culture 3) positive culture. We employed a multivariable logistic regression model to evaluate outcomes.
Results:
We evaluated 78,568 blood cultures in 106,586 admissions. 30-day in-hospital mortality for no culture was 2.8% (95%CI 2.7, 2.9), culture negative 8.9% (95%CI 8.5, 9.3) and culture positive 16.7% (95%CI 15.5, 17.9). There was significant interaction between blood culture category and illness severity, OR 1.06 (95%CI 1.05, 1.08), and comorbidity, OR 1.09 (95%CI 1.09, 1.10).
Conclusion:
Performance and results of blood cultures are independently associated with increased mortality.
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