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Updated: Dec 11, 2025
Preparation of Highly Porous Coordination Polymer Coatings on Macroporous Polymer Monoliths for Enhanced Enrichment of Phosphopeptides
Published on: July 14, 2015
Polyoxometalate-functionalized macroporous microspheres for selective separation/enrichment of glycoproteins
Meng-Meng Wang1, Shuai Chen2, Yong-Liang Yu1
1Research Center for Analytical Sciences, Department of Chemistry, College of Sciences, Northeastern University, Box 332, Shenyang 110819, China. yuyl@mail.neu.edu.cn jianhuajrz@mail.neu.edu.cn.
Abstract:
Glycoproteins always participate in various biological processes. Selective separation and enrichment of glycoproteins are of great significance for the research of pathogenesis. Herein, macroporous polymer microspheres were fabricated, and further functionalized by polyoxometalate. Thus, a simple, efficient and highly selective approach was constructed for glycoprotein enrichment from a complex matrix. The as-prepared material shows promise as a potential adsorbent in bio-separation and downstream clinical applications.
