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Mean Platelet Volume in Type 2 Diabetes Male.

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Mean platelet volume is significantly higher in adult males with type 2 diabetes mellitus. This finding suggests mean platelet volume may help predict cardiovascular risk in diabetic patients.

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Area of Science:

  • Cardiovascular Research
  • Endocrinology
  • Hematology

Background:

  • Diabetes mellitus (DM) prevalence is rising globally, with complications impacting patient health.
  • Altered platelet morphology and function are observed in patients with DM.
  • Mean platelet volume (MPV) is an emerging risk marker for atherothrombosis and cardiovascular disease.

Purpose of the Study:

  • To assess mean platelet volume (MPV) in adult males with type 2 diabetes mellitus.
  • To compare MPV levels between type 2 diabetic males and healthy controls.
  • To evaluate MPV as a potential predictor of cardiovascular risk in diabetic males.

Main Methods:

  • A cross-sectional analytical study involving 200 adult males (40-60 years) in Dhaka, Bangladesh.
  • 100 subjects with type 2 diabetes mellitus (case group) and 100 healthy subjects (control group).
  • Mean platelet volume measured using hematological analysis; data analyzed with SPSS using unpaired Student's 't' test.

Main Results:

  • Mean platelet volume was significantly higher (p<0.001) in the type 2 diabetes mellitus group compared to the control group.
  • This indicates a notable difference in platelet characteristics between diabetic and non-diabetic individuals.
  • The findings support MPV as a potential indicator of increased platelet activity in diabetes.

Conclusions:

  • Estimation of mean platelet volume may be beneficial for predicting future cardiovascular risk in adult males with type 2 diabetes mellitus.
  • Elevated MPV in diabetic patients warrants further investigation for its role in atherothrombosis.
  • MPV serves as a potential, accessible biomarker for cardiovascular risk stratification in diabetic populations.