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Mean Platelet Volume in Type 2 Diabetes Male
1Dr Fayeza Karim, Associate Professor and Head, Department of Physiology, Aichi Medical College, Dhaka, Bangladesh;
Mymensingh Medical Journal : MMJ
|August 27, 2020
Summary
Mean platelet volume is significantly higher in adult males with type 2 diabetes mellitus. This finding suggests mean platelet volume may help predict cardiovascular risk in diabetic patients.
Area of Science:
- Cardiovascular Research
- Endocrinology
- Hematology
Background:
- Diabetes mellitus (DM) prevalence is rising globally, with complications impacting patient health.
- Altered platelet morphology and function are observed in patients with DM.
- Mean platelet volume (MPV) is an emerging risk marker for atherothrombosis and cardiovascular disease.
Purpose of the Study:
- To assess mean platelet volume (MPV) in adult males with type 2 diabetes mellitus.
- To compare MPV levels between type 2 diabetic males and healthy controls.
- To evaluate MPV as a potential predictor of cardiovascular risk in diabetic males.
Main Methods:
- A cross-sectional analytical study involving 200 adult males (40-60 years) in Dhaka, Bangladesh.
- 100 subjects with type 2 diabetes mellitus (case group) and 100 healthy subjects (control group).
- Mean platelet volume measured using hematological analysis; data analyzed with SPSS using unpaired Student's 't' test.
Main Results:
- Mean platelet volume was significantly higher (p<0.001) in the type 2 diabetes mellitus group compared to the control group.
- This indicates a notable difference in platelet characteristics between diabetic and non-diabetic individuals.
- The findings support MPV as a potential indicator of increased platelet activity in diabetes.
Conclusions:
- Estimation of mean platelet volume may be beneficial for predicting future cardiovascular risk in adult males with type 2 diabetes mellitus.
- Elevated MPV in diabetic patients warrants further investigation for its role in atherothrombosis.
- MPV serves as a potential, accessible biomarker for cardiovascular risk stratification in diabetic populations.
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