Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Immunodeficiency Diseases01:25

Immunodeficiency Diseases

1.8K
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
1.8K
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

625
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
625
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

696
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
696
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

240
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
240
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

95
Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
95
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

278
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
278

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rheumatoid meningitis and infection in absence of rheumatoid arthritis history: review of 31 cases.

Clinical rheumatology·2020
Same author

Human immunodeficiency virus infection (HIV)-associated rheumatic manifestations in thepre- and post-HAART eras.

Clinical rheumatology·2020
Same author

Catastrophic antiphospholipid syndrome: is life-long anticoagulation therapy required?

Clinical rheumatology·2020
Same author

Eosinophilic Vasculitis.

Current rheumatology reports·2020
Same author

Role of Inflammasome Activation in Systemic Lupus Erythematosus: Are Innate Immune Cells Activated?

Reumatologia clinica·2020
Same author

Bilateral Dupuytren's Contracture and the "Prayer's Sign".

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases·2020
Same journal

Type I Interferonopathies: Fifteen Years On, From Concept to Therapeutic Perspectives.

Current rheumatology reports·2026
Same journal

Intensive Care Management of ANCA-associated Vasculitides: a Narrative Review.

Current rheumatology reports·2026
Same journal

The Role of Musculoskeletal Ultrasound in Psoriatic Arthritis: From Preclinical Detection to Treatment Monitoring.

Current rheumatology reports·2026
Same journal

Correction to: Is Gout and Autoinflammatory Disease?

Current rheumatology reports·2026
Same journal

Risks and Management of Glucocorticoid Therapy for Patients with Rheumatic Disease Having Surgery.

Current rheumatology reports·2026
Same journal

Perioperative Management Considerations for Patients with Systemic Lupus Erythematosus.

Current rheumatology reports·2026
See all related articles

Related Experiment Video

Updated: Dec 10, 2025

Quantification of Cerebral Vascular Architecture using Two-photon Microscopy in a Mouse Model of HIV-induced Neuroinflammation
10:04

Quantification of Cerebral Vascular Architecture using Two-photon Microscopy in a Mouse Model of HIV-induced Neuroinflammation

Published on: January 12, 2016

9.5K

Vasculitides in HIV Infection.

Luis E Vega1, Luis R Espinoza2

  • 1Section of Rheumatology, Air Force Central Hospital, Aramburú Ave 2nd block, Lima, Peru. luisenvega@gmail.com.

Current Rheumatology Reports
|August 27, 2020
PubMed
Summary
This summary is machine-generated.

Vasculitis remains rare in HIV-positive patients, presenting a spectrum from mild to severe conditions. Early recognition is crucial for appropriate treatment, including potential immunosuppression.

Keywords:
HIV infectionKawasaki-like syndromeLarge-vessel vasculitisPolyarteritis nodosaVasculitides

More Related Videos

Isolation of Exosomes from the Plasma of HIV-1 Positive Individuals
06:46

Isolation of Exosomes from the Plasma of HIV-1 Positive Individuals

Published on: January 5, 2016

17.7K
Peptide-based Identification of Functional Motifs and their Binding Partners
14:28

Peptide-based Identification of Functional Motifs and their Binding Partners

Published on: June 30, 2013

12.9K

Related Experiment Videos

Last Updated: Dec 10, 2025

Quantification of Cerebral Vascular Architecture using Two-photon Microscopy in a Mouse Model of HIV-induced Neuroinflammation
10:04

Quantification of Cerebral Vascular Architecture using Two-photon Microscopy in a Mouse Model of HIV-induced Neuroinflammation

Published on: January 12, 2016

9.5K
Isolation of Exosomes from the Plasma of HIV-1 Positive Individuals
06:46

Isolation of Exosomes from the Plasma of HIV-1 Positive Individuals

Published on: January 5, 2016

17.7K
Peptide-based Identification of Functional Motifs and their Binding Partners
14:28

Peptide-based Identification of Functional Motifs and their Binding Partners

Published on: June 30, 2013

12.9K

Area of Science:

  • Immunology
  • Rheumatology
  • Infectious Diseases

Background:

  • Vasculitis is uncommon in human immunodeficiency virus (HIV)-infected individuals, particularly in the post-highly active antiretroviral therapy (HAART) era.
  • Histopathological studies reveal distinct features in HIV-positive patients, such as leukocytoclastic vasculitis affecting the vasa vasorum and adventitial inflammation in large arteries.
  • HIV-positive patients with large vessel vasculitis (LVV) may experience more vascular complications and poorer outcomes compared to HIV-negative counterparts.

Purpose of the Study:

  • To comprehensively review the range of vasculitides observed in HIV-infected patients.
  • To identify specific clinical characteristics that help diagnose vasculitis in individuals with HIV.

Main Methods:

  • Literature review of epidemiological studies and retrospective cohort studies.
  • Analysis of histopathological findings in HIV-positive patients with vasculitis.
  • Comparison of clinical outcomes between HIV-positive and HIV-negative patients with vasculitis.

Main Results:

  • Vasculitis is a rare but significant condition in HIV-positive individuals.
  • Distinct histopathological findings differentiate vasculitis in HIV-positive patients.
  • HIV-positive patients with LVV may have a less favorable response to antiretroviral therapy and worse prognosis.

Conclusions:

  • Vasculitis in HIV-infected patients encompasses a broad spectrum of disease severity.
  • Timely diagnosis and recognition of vasculitis in HIV-positive individuals are essential.
  • Management may necessitate immunosuppressive therapies in addition to antiretroviral treatment.