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Postbiotics and paraprobiotics: From concepts to applications
P F Cuevas-González1, A M Liceaga2, J E Aguilar-Toalá2
1Unidad Académica Ensenada, Universidad Tecnológica de Tijuana, Carretera a la Bufadora Km 1 Maneadero Parte Alta, Ensenada, Baja California, Mexico.
Food Research International (Ottawa, Ont.)
|August 28, 2020
Summary
Postbiotics and paraprobiotics, non-viable microbial products, offer health benefits. Research explores their bioactivities, production, and applications, highlighting their potential in the nutraceutical industry.
Area of Science:
- Microbiology and Biotechnology
- Nutraceutical Science
- Immunology
Background:
- Emerging concepts like postbiotics and paraprobiotics describe non-viable microbial components or extracts.
- These offer bioactivities beyond traditional probiotics, but their mechanisms are not fully understood.
- Existing research indicates potential health benefits, necessitating further investigation.
Purpose of the Study:
- To provide an overview of postbiotics and paraprobiotics.
- To explore their conceptualization, production, characterization, and bioactivities.
- To discuss emerging trends, health effects, and applications in biotechnology and nutraceuticals.
Main Methods:
- Review of in vitro and in vivo studies on postbiotics and paraprobiotics.
- Analysis of scientific literature on their bioactivities and health-promoting effects.
- Exploration of bioengineering approaches and biotechnological applications.
Main Results:
- Postbiotics and paraprobiotics demonstrate anti-inflammatory, immunomodulatory, anti-proliferative, antioxidant, and antimicrobial bioactivities.
- These bioactivities are linked to observed health benefits in human and clinical trials.
- Mechanisms of action and signaling pathways remain areas for further elucidation.
Conclusions:
- Postbiotics and paraprobiotics show significant potential for developing biotechnological products.
- They can serve as functional ingredients in the nutraceutical industry.
- Further research is needed to fully understand their mechanisms and optimize applications.
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