Cutaneous Metastases from Lung Adenocarcinoma

Area of Science:

• Oncology
• Dermatology
• Pathology

Background:

• Cutaneous metastases from lung cancer are uncommon but can present as a diagnostic challenge.
• Early recognition is crucial for timely and appropriate patient management.

Observation:

• A 49-year-old female presented with a 10-day history of painful, zosteriform rashes on her left breast.
• The lesions were characterized by multiple vesicle-like papules.

Findings:

• The patient had a prior diagnosis of lung adenocarcinoma.
• Skin biopsy revealed dermal nodular lesions with tumor cells forming glandular structures.
• Immunohistochemical stains confirmed metastatic lung adenocarcinoma.

Implications:

• This case underscores the importance of considering cutaneous metastases in patients with a history of lung cancer, even with unusual presentations.
• Zosteriform rashes may be an indicator of metastatic disease, necessitating thorough dermatological and oncological evaluation.
• Accurate diagnosis through skin biopsy and immunohistochemistry is vital for effective treatment planning.