Related Experiment Video
Updated: Dec 10, 2025

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
Published on: May 16, 2025
Adaptive treatment strategies for chronic conditions: shared-parameter G-estimation with an application to rheumatoid
Shouao Wang1, Erica Em Moodie1, David A Stephens2
1Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC Canada, H3A 1A2.
Abstract:
Most estimation algorithms for adaptive treatment strategies assume that treatment rules at each decision point are independent from one another in the sense that they do not possess any common parameters. This is often unrealistic, as the same decisions may be made repeatedly over time. Sharing treatment-decision parameters across decision points offers several advantages, including estimation of fewer parameters and the clinical ease of a single, time-invariant decision to implement. We propose a new computational approach to estimation of shared-parameter G-estimation, which is efficient and shares the double robustness of the "unshared" sequential G-estimation. We use this approach to analyze data from the Scottish Early Rheumatoid Arthritis (SERA) Inception Cohort.
Related Concept Videos
Rheumatic Heart Disease III: Medical Management
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...
Rheumatic Heart Disease IV: Nursing Management
Dosage Regimens: Designs and Approaches
Model Approaches for Pharmacokinetic Data: Distributed Parameter Models
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...
Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration

