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Cardiovascular Manifestations of Systemic Vasculitides

Luis H Silveira1

  • 1Department of Rheumatology, Instituto Nacional de Cardiología Ignacio Chávez, Juan Badiano No. 1, colonia Sección XVI, 14080, Ciudad de México, Mexico. luis_hsil@hayoo.com.

Current Rheumatology Reports
|August 29, 2020
PubMed

Insights

Vasculitis significantly impacts cardiovascular health, increasing risks of heart attack and atherosclerosis. Early detection and treatment of these vascular conditions are crucial for improving patient outcomes and reducing mortality.

Area of Science:

  • Cardiovascular Medicine
  • Rheumatology
  • Immunology

Background:

  • Vasculitis is associated with premature atherosclerosis, leading to increased cardiovascular morbidity and mortality.
  • Understanding the cardiovascular effects of vasculitis is essential for early detection and intervention.

Purpose of the Study:

  • To review the impact of vasculitis on the cardiovascular system.
  • To highlight the importance of early detection and treatment of cardiovascular abnormalities in vasculitis patients.

Main Methods:

  • Review of recent findings on cardiovascular events in vasculitis.
  • Analysis of trends in inpatient burden of myocardial infarction and thromboembolic events.
  • Evaluation of imaging techniques for subclinical cardiovascular involvement.

Main Results:

  • Increasing trends of myocardial infarction and thromboembolic events observed in granulomatosis with polyangiitis.
  • Behçet's disease linked to increased risk of atrial fibrillation.
  • Subclinical cardiovascular involvement is frequent, as shown by advanced imaging.

Conclusions:

  • Vasculitis poses a serious threat to the cardiovascular system, increasing morbidity and mortality.
  • Early immunosuppression and surgical interventions are vital for improving prognosis in vasculitis patients.
  • Prompt management of cardiovascular complications in vasculitis is paramount.
Abstract

Keywords:
Behcet’s diseaseCardiovascular diseaseEosinophilic granulomatosis with polyangiitisHeart diseaseTakayasu arteritisVasculitis

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