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Updated: Dec 10, 2025

Imine Metathesis by Silica-Supported Catalysts Using the Methodology of Surface Organometallic Chemistry
Published on: October 18, 2019
A theoretical review for novel Lewis base amine/imine-catalyzed reactions
Qianqian Deng1, Fangjing Mu, Yan Qiao
1College of Chemistry, and Institute of Green Catalysis, Zhengzhou University, Zhengzhou, Henan 450001, China. donghuiwei@zzu.edu.cn.
Abstract:
Different from the traditional role of a Brønsted base, amines/imines have been widely employed during the past few decades as a Lewis base to activate electrophilic allene, olefin, and carbonyl compounds. Understanding the detailed mechanisms and the origin of chemo- and stereo-selectivities for these types of reactions should be very important and highly desirable. In this minireview, the recent advances and methods for analysis of the origin of the selectivities of novel Lewis base amine/imine-mediated reactions are systematically summarized and reviewed from a theoretical viewpoint. This information provides valuable insights for understanding the general action modes of Lewis base amine/imine catalysts and rational design of more efficient organocatalytic reactions with high stereoselectivity and special chemoselectivity.
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