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Updated: Dec 10, 2025

Swabbing the Urban Environment - A Pipeline for Sampling and Detection of SARS-CoV-2 From Environmental Reservoirs
Published on: April 9, 2021
City lockdown and nationwide intensive community screening are effective in controlling the COVID-19 epidemic:
Tailai Peng1,2, Xinhao Liu1, Hefeng Ni2
1Department of Anesthesiology and Translational Neuroscience Center, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Background:
In December 2019, an outbreak of COVID-19 epidemic occurred in Wuhan, China and infection spread rapidly around the world. To limit the rapid spread locally and nationwide, the Chinese government locked down Wuhan city on January 23 and began implementing nationwide intensive community screening on February 16.
Method:
To assess the effectiveness of city lockdown and intensive community screening, we built a modified SIR model by introducing an α value into the classic SIR model. The α value represents the proportion of infected individuals who are not effectively isolated from susceptible individuals at a given time point.
Results:
The accuracy of the modified SIR model was validated using data from Guangdong and Zhejiang provinces. The lockdown of Wuhan city substantially reduced the α value for the rest of China excluding Hubei province, while only slightly reducing the α value for the city itself. Intensive community screening rapidly reduced the α value for Wuhan.
Conclusion:
City lockdown was efficient in controlling the spread of the epidemic from Wuhan to the rest of the country. Nationwide intensive community screening was extremely effective in suppressing the spread locally within Wuhan city. These experiences should urgently be shared with other countries to help halt the progressing worldwide pandemic.
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