Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Dec 10, 2025

Forebrain Electrophysiological Recording in Larval Zebrafish
06:00

Forebrain Electrophysiological Recording in Larval Zebrafish

Published on: January 24, 2013

17.6K

Learning-dependent neuronal activity across the larval zebrafish brain.

Matthew Lovett-Barron1

  • 1Neurobiology Section, Division of Biological Sciences, University of California, San Diego, La Jolla, CA, USA.

Current Opinion in Neurobiology
|August 30, 2020
PubMed
Summary

Larval zebrafish offer a unique model for studying brain-wide neural networks involved in learning and memory. Their optically accessible nervous system allows researchers to observe distributed activity patterns crucial for understanding experience encoding.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rhomboid protease Rhbdl2 regulates macrophage recruitment and wound regeneration in zebrafish.

bioRxiv : the preprint server for biology·2026
Same author

Convergent thyroid-ATPase interactions regulate collective behavior in Danionella.

Cell reports·2025
Same author

Neuronal detection of social actions directs collective escape behavior.

bioRxiv : the preprint server for biology·2025
Same author

Predator avoidance: Threat learning in week-old zebrafish.

Current biology : CB·2025
Same author

Development of neural circuits for social motion perception in schooling fish.

Current biology : CB·2024
Same author

Understanding collective behavior through neurobiology.

Current opinion in neurobiology·2024

Area of Science:

  • Neuroscience
  • Systems Neuroscience
  • Behavioral Neuroscience

Background:

  • Learning induces widespread neuronal activity changes across the brain.
  • Understanding distributed neural organization for memory encoding is challenging in mammals.
  • Larval zebrafish present an optically accessible model system for brain-wide studies.

Purpose of the Study:

  • To review the potential of larval zebrafish for studying brain-wide learning and memory networks.
  • To discuss opportunities and challenges in using zebrafish for memory research.
  • To explore how zebrafish neurotechnology can elucidate principles of distributed memory.

Main Methods:

  • Review of existing literature on larval zebrafish neurobiology and learning.
  • Analysis of brain-wide imaging techniques in zebrafish during behavioral tasks.

More Related Videos

Author Spotlight: In Vivo Whole-Brain Imaging of Zebrafish Larvae Using Three-Dimensional Fluorescence Microscopy
06:27

Author Spotlight: In Vivo Whole-Brain Imaging of Zebrafish Larvae Using Three-Dimensional Fluorescence Microscopy

Published on: April 28, 2023

5.4K
Author Spotlight: Advancements in Adult Zebrafish Brain Research
07:21

Author Spotlight: Advancements in Adult Zebrafish Brain Research

Published on: July 28, 2023

3.5K

Related Experiment Videos

Last Updated: Dec 10, 2025

Forebrain Electrophysiological Recording in Larval Zebrafish
06:00

Forebrain Electrophysiological Recording in Larval Zebrafish

Published on: January 24, 2013

17.6K
Author Spotlight: In Vivo Whole-Brain Imaging of Zebrafish Larvae Using Three-Dimensional Fluorescence Microscopy
06:27

Author Spotlight: In Vivo Whole-Brain Imaging of Zebrafish Larvae Using Three-Dimensional Fluorescence Microscopy

Published on: April 28, 2023

5.4K
Author Spotlight: Advancements in Adult Zebrafish Brain Research
07:21

Author Spotlight: Advancements in Adult Zebrafish Brain Research

Published on: July 28, 2023

3.5K
  • Discussion of neurotechnological advancements for studying neural networks.

    • Main Results:

    • Larval zebrafish provide a tractable model for observing experience-dependent neural activity.
    • Recent studies demonstrate the feasibility of brain-wide imaging in zebrafish.
    • Zebrafish research offers insights into the physiological basis of distributed memory.

    Conclusions:

    • The larval zebrafish nervous system is a powerful tool for investigating brain-wide memory mechanisms.
    • Further research using zebrafish can bridge the gap between neural activity and behavioral significance.
    • Zebrafish neurotechnology holds promise for advancing our understanding of distributed memory networks.