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In Vivo Imaging Systems IVIS Detection of a Neuro-Invasive Encephalitic Virus

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Acute necrotizing encephalopathy: A case report.

Evan L Jackson¹, Wesley Eilbert¹, Amber M Hathcock²

¹Department of Emergency Medicine, University of Illinois, College of Medicine, 1819 West Polk St. Room 469, Chicago, IL 60612, United States of America.

The American Journal of Emergency Medicine

|August 31, 2020

Summary

This summary is machine-generated.

Acute necrotizing encephalopathy (ANE) is a rare pediatric brain disorder. Early diagnosis via clinical and imaging findings is crucial for prompt treatment and improved outcomes in children.

Keywords:

Acute necrotizing encephalopathy Necrotizing encephalopathy Post-infectious encephalopathy Viral encephalopathy

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Area of Science:

Neurology
Pediatrics
Infectious Diseases

Background:

Acute necrotizing encephalopathy (ANE) is an uncommon, severe neurological disorder primarily affecting children.
It typically follows a viral infection and presents with seizures and rapid neurological decline.
Diagnosis relies on clinical symptoms and characteristic brain imaging findings.

Observation:

A previously healthy two-year-old boy experienced seizures, fever, and diarrhea.
The patient presented to the emergency department with these symptoms.

Findings:

Diagnosis was confirmed as ANE based on clinical presentation and characteristic multifocal brain lesions on CT scans.
Treatment involved corticosteroids and intravenous immunoglobulin (IVIG).

Implications:

Early identification of ANE is critical due to its potential for high morbidity.
Recognizing the typical clinical and radiological features facilitates timely and optimal management.