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Updated: Dec 10, 2025

Construction and Characterization of a Novel Vocal Fold Bioreactor
Published on: August 1, 2014
Does Voice Therapy Improve Vocal Outcomes in Vocal Fold Atrophy?
Emma Bick1, Lukas D Dumberger1, Douglas R Farquhar2
1University of North Carolina School of Medicine, Chapel Hill, NC, USA.
Voice therapy significantly improves vocal fold atrophy outcomes, including quality of life and voice function, though compliance remains low. Surgical patients present with different pre-treatment vocal characteristics.
Area of Science:
- Gerontology
- Otolaryngology
- Speech-Language Pathology
Background:
- Vocal fold atrophy is a growing concern in the elderly population.
- Outcomes of voice therapy for vocal fold atrophy vary, necessitating further analysis.
- Multidimensional vocal assessments are crucial for understanding treatment efficacy.
Purpose of the Study:
- To analyze multidimensional vocal outcomes in patients with vocal fold atrophy undergoing voice therapy.
- To determine patient compliance with recommended voice therapy.
- To compare outcomes between patients receiving voice therapy and those undergoing surgery.
Main Methods:
- A retrospective review of 197 patients diagnosed with vocal fold atrophy.
- Categorization of patients based on treatment received: no therapy, incomplete therapy, complete therapy, surgery only, or therapy followed by surgery.
- Analysis of patient-reported, perceptual, aerodynamic, and acoustic voice outcomes pre- and post-intervention using Wilcoxon signed-rank and rank-sum tests.
Main Results:
- Only 29% of patients completed recommended voice therapy.
- Complete voice therapy led to significant improvements in voice-related quality of life (VRQOL), glottal function index (GFI), GRBAS scores, maximum phonation time (MPT), and fundamental frequency in women.
- No significant changes were observed in mean airflow. Pre-treatment VRQOL and GFI differed significantly between surgery and voice therapy groups.
Conclusions:
- Voice therapy demonstrates significant multidimensional benefits for patients with vocal fold atrophy.
- Low compliance with voice therapy recommendations is a key challenge in this population.
- Pre-treatment patient-reported measures distinguish surgical candidates from those treated with voice therapy alone.
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