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Related Experiment Videos

Do protein and phosphorus cause calcium loss?

H Spencer1, L Kramer, D Osis

  • 1Metabolic Research, Veterans Administration Hospital, Hines, IL 60141.

The Journal of Nutrition
|June 1, 1988
PubMed
Summary

Common dietary proteins and phosphorus do not cause calcium loss in adults. However, low protein and phosphorus diets may negatively impact calcium balance, especially in the elderly.

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Area of Science:

  • Nutrition Science
  • Human Metabolism
  • Bone Health

Background:

  • Widespread belief suggests dietary protein and phosphorus deplete calcium stores.
  • Understanding the impact of these nutrients on calcium metabolism is crucial for public health.
  • Existing research has yielded conflicting results regarding protein and phosphorus effects on calcium balance.

Purpose of the Study:

  • To critically examine the common belief that dietary protein and phosphorus lead to calcium loss.
  • To evaluate the effects of varying protein and phosphorus intakes on calcium metabolism in adult humans.
  • To investigate potential adverse effects of low protein and phosphorus diets on calcium balance, particularly in the elderly.

Main Methods:

  • Review of controlled human studies investigating the relationship between protein, phosphorus, and calcium metabolism.
  • Analysis of data from studies involving adult human subjects with varying dietary intakes.
  • Examination of the impact of phosphorus from different sources, including carbonated beverages.

Main Results:

  • Complex dietary proteins, even with high phosphorus content, do not induce calcium loss in adult humans.
  • Phosphorus intake up to 2000 mg/day shows no adverse effects on calcium metabolism in adults.
  • Diets deficient in both protein and phosphorus may negatively affect calcium balance in elderly individuals.

Conclusions:

  • The prevailing notion that high protein and phosphorus intake causes calcium loss is not supported by evidence from controlled human studies in adults.
  • Dietary phosphorus, within typical intake ranges, appears safe for calcium metabolism, though beverage phosphates warrant further investigation.
  • Maintaining adequate protein and phosphorus intake is important for preserving calcium balance, particularly in older adults.

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