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Updated: Dec 10, 2025

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
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Synthesis and Reactivity of Fluorinated Triaryl Aluminum Complexes
Darren M C Ould1, Jamie L Carden1, Rowan Page1
1Cardiff Catalysis Institute, School of Chemistry, Cardiff University, Main Building, Cardiff CF10 3AT, Cymru/Wales, U.K.
Abstract:
The addition of the Grignard 3,4,5-ArFMgBr to aluminum(III) chloride in ether generates the novel triarylalane Al(3,4,5-ArF)3·OEt2. Attempts to synthesize this alane via transmetalation from the parent borane with trimethylaluminum gave a dimeric structure with bridging methyl groups, a product of partial transmetalation. On the other hand, the novel alane Al(2,3,4-ArF)3 was synthesized from the parent borane and trimethylaluminum. Interestingly, the solid-state structure of Al(2,3,4-ArF)3 shows an extended chain structure resulting from neighboring Al···F contacts. Al(3,4,5-ArF)3·OEt2 was then found to be an effective catalyst for the hydroboration of carbonyls, imines, and alkynes with pinacolborane.
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