Related Experiment Video
Updated: Dec 10, 2025

Characterization of Immune Cell-derived Extracellular Vesicles and Studying Functional Impact on Cell Environment
Published on: June 2, 2020
Impact of Avène Thermal Spring Water on immune cells
Y Eliasse1,2, D Redoules3, E Espinosa1,2
1Inserm U1037, Centre de Recherche en Cancérologie de Toulouse (CRCT), Toulouse, France.
Abstract:
The hydrotherapy centre in Avène, France, is used extensively to treat inflammatory skin diseases. Nevertheless, the immune mechanisms targeted by Avène Thermal Spring Water (TSW) are not fully understood. Here, we review the main results reported regarding the effects of Avène TSW on the immune system. In particular, mast cells, dendritic cells (DCs) and CD4+ T cells have been shown to be modulated by Avène TSW. All in all, the studies carried out on the effects of Avène TSW on leucocytes indicate that this water is endowed with a tolerogenic potential.
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