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Astigmatism-corrected endoscopic imaging probe for optical coherence tomography using soft lithography.

Min Woo Lee, Yeon Hoon Kim, Jingchao Xing

|September 2, 2020

Summary

We developed a novel, cost-effective imaging probe for endoscopic optical coherence tomography that corrects astigmatism. This innovation improves image quality and reduces probe size, overcoming limitations of existing methods.

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Area of Science:

Biomedical Optics
Medical Imaging Technology
Optical Engineering

Background:

Endoscopic optical coherence tomography (OCT) utilizes protective sheaths that induce astigmatism.
This astigmatism degrades image quality by reducing transverse resolution and signal-to-noise ratio.
Current astigmatism correction methods are complex, expensive, and increase probe size.

Purpose of the Study:

To develop a simple, cost-effective, and compact astigmatism-corrected imaging probe for endoscopic OCT.
To overcome the limitations of existing astigmatism correction techniques in OCT probes.

Main Methods:

Fabrication of an imaging probe featuring an epoxy window using soft lithography.
Precise adjustment of astigmatism by controlling the epoxy window's curvature radius.
Integration of the epoxy window using simple fiber optic fusion splicing for a monolithic probe.

Main Results:

Demonstrated precise and cost-effective astigmatism correction via epoxy window curvature.
Achieved a monolithic probe design with a diameter comparable to standard single-mode fiber.
Validated the probe's performance through focal spot analysis, micro-bead imaging, and biological sample imaging.

Conclusions:

The developed epoxy window probe effectively corrects astigmatism in endoscopic OCT.
This approach offers a simple, low-cost, and miniaturized solution for improved OCT imaging.
The technology has potential to enhance diagnostic capabilities in endoscopic procedures.