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Acute Pulmonary Embolism in COVID-19: A Report of Two Cases

Yashvin Onkarappa Mangala1, Saravgunjit Singh Daid1, Seetha Lakshmanan2

  • 1Internal Medicine, Roger Williams Medical Center, Providence, USA.

Cureus
|September 3, 2020
PubMed

Insights

Coronavirus disease 2019 (COVID-19) is linked to blood clot risks like venous thromboembolism (VTE). This study examines two non-ICU COVID-19 patients with pulmonary embolism (PE) and discusses anticoagulation management.

Area of Science:

  • Internal Medicine
  • Cardiology
  • Pulmonology

Background:

  • Coronavirus disease 2019 (COVID-19) is associated with abnormal coagulation and a hyper-coagulable state.
  • This hyper-coagulable state increases the risk of venous thromboembolism (VTE) in COVID-19 patients.

Observation:

  • Presents two cases of non-intensive care unit (non-ICU) patients with COVID-19.
  • Both cases developed acute pulmonary embolism (PE) as a complication.

Findings:

  • Current guidelines for anticoagulation in COVID-19 patients with VTE are not well-established.
  • Discusses the pathophysiology of coagulation abnormalities in COVID-19.
  • Reviews management strategies for anticoagulation in these patients based on recent literature.

Implications:

  • Highlights the need for clear anticoagulation guidelines in non-ICU COVID-19 patients who develop VTE.
  • Emphasizes the importance of considering VTE risk and management in a broader range of COVID-19 patients.
  • Contributes to the understanding of COVID-19's impact on coagulation and clinical management strategies.

Keywords:
acute pulmonary embolismanticoagulationcovid 19venous thromboembolism (vte)

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