A corneal ring ulcer
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Updated: Dec 10, 2025
Corneal Epithelial Abrasion with Ocular Burr As a Model for Cornea Wound Healing
Published on: July 10, 2018
Khaled Alhajraf1, Shawn R Lin2, Deborah S Jacobs1
1Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.
Purpose:
The aim of this report is to present the case of a corneal ring ulcer that presented with diagnostic and therapeutic challenges.
Observations:
A 52-year-old woman was referred by her retina doctors for ulceration of the left cornea and pain 8 days after intravitreal ranibizumab injection for diabetic macular edema. She had been treated with erythromycin ointment, topical moxifloxacin, and therapeutic soft contact lens, which she tolerated for less than 24 hours prior to referral. Visual acuity of the left eye was counting fingers. Slit lamp examination revealed a ring-shaped corneal ulcer.
Conclusions:
Neurotrophic corneal ulceration can mimic acanthamoeba keratitis. Neurotrophic disease should be considered in patients with underlying risk factors in whom infectious etiology cannot be confirmed and/or who don't respond to anti-microbial therapy.
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