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Heart Failure in Humans Reduces Contractile Force in Myocardium From Both Ventricles

Cheavar A Blair1, Elizabeth A Brundage2, Katherine L Thompson3

  • 1Department of Physiology, University of Kentucky, Lexington, Kentucky.

JACC. Basic to Translational Science
|September 3, 2020
PubMed

Keywords:
Ca2+ sensitivityCa2+, calciumFact, maximum Ca2+-activated forceFpas, passive forceLV, left ventricleMyBP-C, myosin binding protein-CPKA, protein kinase APmax, maximum power outputRLC, regulatory light chainRV, right ventricleTnI, troponin IVmax, maximum shortening velocityheart failurehuman myocardiumktr, rate of force recoverymyofilament proteinsnH, Hill coefficientventricular function

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