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Published on: September 22, 2023
Rethinking gastroesophageal reflux disorder
Samuel P Banting1, Henry E Badgery2, Matthew Read2,3
1Department of General Surgery, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Abstract:
Gastroesophageal reflux disease (GERD) is a common clinical condition for which our understanding has evolved over the past decades. It is now considered a cluster of phenotypes with numerous anatomical and physiological abnormalities contributing to its pathophysiology. As such, it is important to first understand the underlying mechanism of the disease process for each patient before embarking on therapeutic interventions. The aim of our paper is to highlight the mechanisms contributing to GERD and review investigations and interpretation of these results. Finally, the paper reviews the available treatment modalities for this condition, ranging from medical intervention, endoscopic options through to surgery and its various techniques.
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