Related Experiment Video

Updated: Dec 10, 2025

3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats
08:22

3D Cine Magnetic Resonance Imaging of Respiratory Motion in Mechanically Ventilated Mice and Rats

Published on: September 19, 2025

812

ADVERSE EVENTS RELATED TO MECHANICAL VENTILATION IN A PEDIATRIC INTENSIVE CARE UNIT

Lana Dos Santos Martins1, Alexandre Rodrigues Ferreira2, Fabiana Maria Kakehasi2

  • 1Pediatric Intensive Care Unit, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.

Revista Paulista De Pediatria : Orgao Oficial Da Sociedade De Pediatria De Sao Paulo
|September 3, 2020
PubMed

Insights

Adverse events (AE) during invasive mechanical ventilation in the Pediatric Intensive Care Unit (PICU) affect 21.6% of patients. Post-extubation stridor and unplanned extubation are common, with longer hospital stays increasing AE risk.

Area of Science:

  • Pediatric critical care medicine
  • Patient safety
  • Mechanical ventilation

Background:

  • Invasive mechanical ventilation is crucial for critically ill children.
  • Adverse events (AE) can complicate ventilation and impact outcomes.
  • Understanding AE prevalence and risk factors is vital for improving care in the Pediatric Intensive Care Unit (PICU).

Purpose of the Study:

  • To determine the prevalence of adverse events (AE) in pediatric patients receiving invasive mechanical ventilation.
  • To identify factors associated with the occurrence of AE in this population.
  • To inform strategies for reducing AE in the PICU.

Main Methods:

  • A cross-sectional study was conducted over two years in a tertiary public hospital's PICU.
  • Data on patient demographics, clinical status, ventilation parameters, and AE were collected.
  • Logistic regression analysis was employed to identify factors associated with AE.

Main Results:

  • A total of 306 patients were analyzed, with 21.6% experiencing at least one AE.
  • The most frequent AE were post-extubation stridor (25.9%) and unplanned extubation (16.9%).
  • A length of stay of 7 days or more was significantly associated with a higher occurrence of AE (OR=2.6).

Conclusions:

  • A substantial proportion of pediatric patients on invasive mechanical ventilation experience preventable adverse events.
  • Post-extubation stridor and unplanned extubation are key AE requiring attention.
  • Longer hospitalization duration is a significant risk factor for AE, highlighting the need for targeted interventions.
Abstract

More Related Videos

Mechanical Ventilation Boot Camp Curriculum07:36

Mechanical Ventilation Boot Camp Curriculum

Published on: March 12, 2018

10.5K
Author Spotlight: Unraveling the Impact of Mechanical Ventilation on Diaphragm Function and Patient Outcomes05:51

Author Spotlight: Unraveling the Impact of Mechanical Ventilation on Diaphragm Function and Patient Outcomes

Published on: November 3, 2023

7.9K

Related Concept Videos

Mechanical Ventilation II: Invasive Ventilation01:23

Mechanical Ventilation II: Invasive Ventilation

Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
482
Mechanical Ventilation I: Indication and Settings01:29

Mechanical Ventilation I: Indication and Settings

Mechanical ventilation is a life-saving technique for managing acute respiratory failure and other respiratory complications. The process involves using a machine known as a ventilator to supply oxygen to the lungs and assist in removing carbon dioxide. It serves as a bridge to long-term mechanical ventilation or a temporary measure until ventilatory support is discontinued. The ventilator can maintain this function for a prolonged period, providing critical support for patients until they can...
2.1K
Mechanical Ventilation III: Noninvasive Ventilation01:23

Mechanical Ventilation III: Noninvasive Ventilation

Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation...
406
Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
339
Acute Respiratory Failure-III01:30

Acute Respiratory Failure-III

Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
590
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
856